AKTIP disease associations
AKTIP [ENSP00000300245]
AKT-interacting protein; Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
Synonyms: AKTIP, A0A024R6S6, A0A024R6T5, FTS, H3BM79 ...