ARRDC4 disease associations
ARRDC4 [ENSP00000268042]
Arrestin domain-containing protein 4; Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (By similarity). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (Probable). Through an ubiquitination-dependent mechanism plays also a role in the incorporation of SLC11A2 into extracellular vesicles (By similarity). May play a role in glucose uptake . ; Belongs to the arrestin family.
Synonyms: ARRDC4, ARRDC4p, hARRDC4, A0A024RC80, Q8NCT1 ...