DISEASES

Disease-gene associations mined from literature

PI3 disease associations

PI3 [ENSP00000243924]

Elafin; Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Has been shown to inhibit the alpha-4-beta-2/CHRNA2-CHRNB2 nicotinic acetylcholine receptor and to produce a weak inhibition on Kv11.1/KCNH2/ERG1 and on the transient receptor potential cation channel subfamily V member 1 (TRPV1) .

Synonyms:  PI3,  PI3p,  hPI3,  P19957,  P19957p ...

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