DISEASES

Disease-gene associations mined from literature

PRDM2 disease associations

PRDM2 [ENSP00000235372]

PR domain zinc finger protein 2; S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA- responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.

Synonyms:  PRDM2,  PRDM2p,  hPRDM2,  D6RAA0,  D6RED5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM