DISEASES

Disease-gene associations mined from literature

CEACAM5 disease associations

CEACAM5 [ENSP00000221992]

Carcinoembryonic antigen-related cell adhesion molecule 5; Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 . Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells . ; Belongs to the immunoglobulin superfamily. CEA family.

Synonyms:  CEACAM5,  CEACAM5p,  hCEACAM5,  A0A024R0K5,  A0A087WYX0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM