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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000231454':
IL5 - Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells; Belongs to the IL-5 family.
[a.k.a. R-HSA-912526, IL5-202, XM_011543373.2]
2) '9606.ENSP00000363852':
SLC44A1 - Choline transporter-like protein 1; Choline transporter. May be involved in membrane synthesis and myelin production; Belongs to the CTL (choline transporter-like) family.
[a.k.a. OMIM:606105, AL450265, ENSP00000363852]
3) '9606.ENSP00000302324':
RNASE3 - Eosinophil cationic protein; Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
[a.k.a. OMIM:131398, Eosinophil cationic protein, 4OWZ]
4) '9606.ENSP00000231449':
IL4 - Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages (By similarity). Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4 (By [...]
[a.k.a. BC066277, NX_P05112, BC070123]
5) '9606.ENSP00000336752':
FIP1L1 - Pre-mRNA 3'-end-processing factor FIP1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex.
[a.k.a. XP_016864158.1, Q6UN15, Q49AU3]
6) '9606.ENSP00000443168':
STH - Saitohin.
[a.k.a. uc002ijy.2, NM_001007532.2, AAO03577.1]
7) '9606.ENSP00000412237':
IL10 - Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro- inflammatory cytokines i [...]
[a.k.a. uc001hen.2, ENST00000664374, ENSP00000499664]
8) '9606.ENSP00000229135':
IFNG - Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.
[a.k.a. ENSG00000111537, IFNG-201, NM_000619]
9) '9606.ENSP00000359295':
DR1 - Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
[a.k.a. NX_Q01658, NP_001929.1, NM_001938]
10) '9606.hsa-miR-6090':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -