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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000217386':
OXT - Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin.
[a.k.a. R-HSA-388396, Oxytocin/neurophysin I prepropeptide, AAA59979.1]
2) '9606.ENSP00000241014':
MAPK8IP1 - C-Jun-amino-terminal kinase-interacting protein 1; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. Cytoplasmic MAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun. May also participate in ApoER2-specific reelin signaling. Directly, or indirectly, regulates GLUT2 gene expression and beta-cell function. A [...]
[a.k.a. 5LW1, ENST00000241014.6, Q9UQF2]
3) '9606.ENSP00000312631':
INSM1 - Insulinoma-associated protein 1; Sequence-specific DNA-binding transcriptional regulator that plays a key role in neurogenesis and neuroendocrine cell differentiation during embryonic and/or fetal development. Binds to the consensus sequence 5'-[TG][TC][TC][TT][GA]GGG[CG]A-3' in target promoters. Acts as a transcriptional repressor of NEUROD1 and INS expression via its interaction with cyclin CCND1 in a cell cycle- independent manner. Negatively regulates skeletal muscle-specific gene expression in endocrine cells of the pituitary by inhibiting the Notch signaling pathway. Represses ta [...]
[a.k.a. INSM transcriptional repressor 1, ENSP00000366500, R-HSA-210746]
4) '9606.LINC00374':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000295718':
PTPRN - Receptor-type tyrosine-protein phosphatase-like N; Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets (By similarity). Required for the accumulation of normal levels of insulin- containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain (By similarity). In females, but not in males, required for normal accumulatio [...]
[a.k.a. URS0000D6DDDD, ENSP00000386638, UPI00018819A7]
6) '9606.ENSP00000363360':
INIP - SOSS complex subunit C; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
[a.k.a. MISE, NP_001316514, 58493]
7) '9606.ENSP00000221496':
AMH - Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
[a.k.a. P03971, R-HSA-162582, 268]
8) '9606.ENSP00000358945':
OPN1MW2 - Medium-wave-sensitive opsin 2; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
[a.k.a. NM_001048181.2, ENST00000369929, ENSP00000358945]
9) '9606.ENSP00000346839':
FN1 - Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
[a.k.a. R-HSA-2129379, Q96KP9, ENST00000492816]
10) '9606.LINC00895':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
