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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000427407':
SMIM20 - Small integral membrane protein 20; [Small integral membrane protein 20]: Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Promotes the progression of complex assembly after the association of MT-CO1/COX1 with COX4I1 and COX6C. Chaperone-like assembly factor required to stabilize newly synthesized MT-CO1/COX1 and to prevent its premature turnover. [Phoenixin-20]: Peptide involved in a broad spectrum of regulatory functions (By similarity). Is a ligand for GPR173 (B [...]
[a.k.a. MITRAC7, Small integral membrane protein 20, OTTHUMG00000160330]
2) '9606.ENSP00000387006':
CWC22 - Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. Belongs to the CWC22 family.
[a.k.a. 5XJC, OMIM:615186, fSAPb]
3) '9606.ENSP00000390600':
SCN10A - Sodium channel protein type 10 subunit alpha; Tetrodotoxin-resistant channel that mediates the voltage- dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.
[a.k.a. ENST00000644826.1, XP_011532295.1, ENST00000389803]
4) '9606.hsa-miR-202-5p':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000378409':
VSIR - V-type immunoglobulin domain-containing suppressor of T-cell activation; Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14- mediated MMP2 activation.
[a.k.a. A1L0X9, VSIR-203, ENST00000394957.7]
6) '9606.ENSP00000220562':
EXTL3 - Exostosin-like 3; Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation.
[a.k.a. EC 2.4.1.224, HGNC:3518, exostosin like glycosyltransferase 3]
7) '9606.ENSP00000379350':
ITGB1 - Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...]
[a.k.a. R-HSA-2129379, GPIIA, R-HSA-202733]
8) '9606.hsa-miR-202-3p':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
9) '9606.ENSP00000259915':
POU5F1 - POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily.
[a.k.a. OTF3, ENST00000448657, OCT4]
10) '9606.TRN-GTT2':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
