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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000370625':
POLR2B - DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...]
[a.k.a. R-HSA-162587, R-HSA-6781823, NM_000938]
2) '9606.NTM-IT':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
3) '9606.ENSP00000485527':
CBSL - Cystathionine beta-synthase like.
[a.k.a. NM_001354015, UPI0000169740, NP_001340937.1]
4) '9606.ENSP00000381231':
CBS - Cystathionine beta-synthase-like protein; Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.
[a.k.a. CBS-213, CBS-201, XP_016883979.1]
5) '9606.ENSP00000413436':
RPL10 - 60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development.
[a.k.a. R-HSA-72737, NP_001290555.1, ENST00000406022.6]
6) '9606.SNORD14':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000339723':
CIR1 - Corepressor interacting with RBPJ 1; May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.
[a.k.a. AF098297, BC046098, URS0000D6ECB9]
8) '9606.ENSP00000305426':
TUB - Tubby protein homolog; Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.
[a.k.a. ENST00000305253, TUB_HUMAN, XM_011520344]
9) '9606.ENSP00000360797':
CARD9 - Caspase recruitment domain-containing protein 9; Adapter protein that plays a key role in innate immune response to a number of intracellular pathogens, such as C.albicans and L.monocytogenes. Is at the crossroads of ITAM-tyrosine kinase and the Toll-like receptors (TLR) and NOD2 signaling pathways. Probably controls various innate immune response pathways depending on the intracellular pathogen. In response to L.monocytogenes infection, acts by connecting NOD2 recognition of peptidoglycan to downstream activation of MAP kinases (MAPK) without activating NF-kappa-B. Also involved in ac [...]
[a.k.a. A0A024R8I4, caspase recruitment domain family, member 9, ENSP00000493113]
10) '9606.ENSP00000317310':
CABP1 - Calcium-binding protein 1; Modulates calcium-dependent activity of inositol 1,4,5- triphosphate receptors (ITPRs). Inhibits agonist- induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C- terminal domain of CACNA1C, but has an opposite effect on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). In [...]
[a.k.a. XM_017020239.2, ENSP00000288615, XM_017020235.1]
