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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000221930':
TGFB1 - Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]
[a.k.a. R-HSA-2129379, R-HSA-170834, ENST00000221930.5]
2) '9606.ENSP00000375081':
TSSK1B - Testis-specific serine/threonine-protein kinase 1; Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
[a.k.a. TSSK-1, Testis-specific kinase 1, NP_114417.1]
3) '9606.ENSP00000322788':
MMP1 - 22 kDa interstitial collagenase; Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
[a.k.a. R-HSA-202733, 4AUO, CLG]
4) '9606.hsa-miR-3606-3p':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000310036':
CD34 - Hematopoietic progenitor cell antigen CD34; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
[a.k.a. Q5JTA5, ENST00000367037, 947]
6) '9606.ENSP00000472998':
SNRNP70 - U1 small nuclear ribonucleoprotein 70 kDa; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. [Isoform 4]: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.
[a.k.a. ENSG00000104852, NM_003089.6, ENST00000221448]
7) '9606.ENSP00000356954':
CCN2 - CCN family member 2; Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor- induced DNA synthesis; Belongs to the CCN family.
[a.k.a. AAK60505.1, AF316367, HGNC:2500]
8) '9606.ENSP00000231449':
IL4 - Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages (By similarity). Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4 (By [...]
[a.k.a. BC066277, NX_P05112, BC070123]
9) '9606.ENSP00000271651':
CTSK - Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.
[a.k.a. NM_000396.4, 5TUN, 5Z5O]
10) '9606.ENSP00000297268':
COL1A2 - Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family.
[a.k.a. R-HSA-202733, P08123, R-HSA-6806834]
