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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000241651':
MYOG - Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...]
[a.k.a. CAA35641.1, Myogenin, P15173]
2) '9606.ENSP00000480322':
CD99L2 - CD99 antigen-like protein 2; Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 (By similarity). Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity); Belongs to the CD99 family.
[a.k.a. NM_001242614.1, R-HSA-202733, UNQ1964/PRO4486]
3) '9606.ENSP00000370588':
CD99 - CD99 antigen; Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity).
[a.k.a. ENSP00000405544, R-HSA-202733, NM_001321367.1]
4) '9606.ENSP00000352835':
MB - Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
[a.k.a. ENSP00000352835, NM_203377, ENST00000447607]
5) '9606.ENSP00000310036':
CD34 - Hematopoietic progenitor cell antigen CD34; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
[a.k.a. Q5JTA5, ENST00000367037, 947]
6) '9606.ENSP00000354826':
CALD1 - Caldesmon; Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosi [...]
[a.k.a. NP_149347.2, CALD1-209, ENST00000472096]
7) '9606.ENSP00000250003':
MYOD1 - Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).
[a.k.a. uc001mni.4, EAW68427.1, HPA078647]
8) '9606.RP11-616M22.7':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
9) '9606.ENSP00000338796':
SSX2 - SSX family member 2.
[a.k.a. CCDS14344, CAA60111.1, NP_001265626.1]
10) '9606.ENSP00000258149':
MDM2 - E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...]
[a.k.a. ENSP00000377067, ENSP00000340649, UPI0003F482C4]
