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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000482180':
C11orf95 - Uncharacterized protein C11orf95; Chromosome 11 open reading frame 95.
[a.k.a. A0A087X051, C11orf95-202, C9JLR9]
2) '9606.ENSP00000344666':
NF2 - Merlin; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF [...]
[a.k.a. ENST00000403999, AAK54163.1, ENST00000403435]
3) '9606.LINC01445':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
4) '9606.ENSP00000436836':
CACNG5 - Voltage-dependent calcium channel gamma-5 subunit; Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity).
[a.k.a. UPI001156172E, CCG5_HUMAN, ENSP00000169565]
5) '9606.ENSP00000478927':
YAP1 - Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncopro [...]
[a.k.a. NM_001195044.1, 5YDX, EAW67015.1]
6) '9606.ENSP00000342680':
EZHIP - EZH inhibitory protein; Inhibits PRC2/EED-EZH2 complex function thereby causing down- regulation of H3K27me3. In the PRC2/EED-EZH2 complex, interacts and inhibits EZH2 methyltransferase activity.
[a.k.a. ENSP00000342680, NM_203407.2, HGNC:33738]
7) '9606.ENSP00000281043':
MYCN - N-myc proto-oncogene protein; Positively regulates the transcription of MYCNOS in neuroblastoma cells.
[a.k.a. NP_001280160.1, ENST00000321155, AAA36371.1]
8) '9606.ENSP00000416040':
KIAA1549 - UPF0606 protein KIAA1549; KIAA1549; Belongs to the UPF0606 family.
[a.k.a. UPI0001837EBD, CAQ43114.1, ENSG00000122778]
9) '9606.ENSP00000384273':
RELA - Transcription factor p65; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric RELA-NFKB1 complex appears to be most abundant one. The dimers bind at kap [...]
[a.k.a. ENSP00000435531, R-HSA-983705, ENSP00000437137]
10) '9606.LINC00880':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
