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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000437402':
ENO2 - Gamma-enolase; Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium- dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).
[a.k.a. Enolase 2, AK295220, ENST00000537838]
2) '9606.ENSP00000250092':
CD68 - Macrosialin; Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
[a.k.a. BAF82927.1, CH471108, CAB072862]
3) '9606.ENSP00000314129':
TFE3 - Transcription factor E3; Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3') (By similarity). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF (By similarity). In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity (By similarity). Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also bin [...]
[a.k.a. Q92757, ENSP00000314129, OTTHUMG00000022690]
4) '9606.ENSP00000380093':
SOX10 - Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3.
[a.k.a. EAW60205.1, ENSP00000215964, ENST00000396884]
5) '9606.ENSP00000400142':
EWSR1 - RNA-binding protein EWS; Might normally function as a transcriptional repressor. EWS- fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes; Belongs to the RRM TET family.
[a.k.a. XP_016884146.1, XP_011528300, ENST00000444626]
6) '9606.ENSP00000433847':
B3GAT1 - Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo- fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl- sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regar [...]
[a.k.a. AB029396, XP_024304207.1, XP_016873040]
7) '9606.ENSP00000347454':
ANO1 - Anoctamin-1; Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. Belongs to the anoctamin family.
[a.k.a. ENST00000355303.9, ENST00000529636.5, ANO1_HUMAN]
8) '9606.ENSP00000310036':
CD34 - Hematopoietic progenitor cell antigen CD34; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
[a.k.a. Q5JTA5, ENST00000367037, 947]
9) '9606.RP11-616M22.7':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000352835':
MB - Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
[a.k.a. ENSP00000352835, NM_203377, ENST00000447607]