Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
payload active
DISEASES
The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
<- Back
⤓ Mapping
Continue ->
1) '9606.ENSP00000254322':
DNAJB1 - DnaJ homolog subfamily B member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro).
[a.k.a. 4WB7, ENST00000598235.1, NM_001313964]
2) '9606.ENSP00000379138':
AFP - Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties; Belongs to the ALB/AFP/VDB family.
[a.k.a. CHEMBL3712864, NP_001125.1, 174]
3) '9606.ENSP00000309591':
PRKACA - cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]
[a.k.a. 4WB7, AAG35720.1, R-HSA-388396]
4) '9606.ENSP00000329243':
KRT7 - Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family.
[a.k.a. 4XIF, CK-7, URS00008BC711]
5) '9606.ENSP00000256010':
NTS - Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle; Belongs to the neurotensin family.
[a.k.a. R-HSA-388396, BC010918, CR541936]
6) '9606.ENSP00000265717':
PRKAR2B - cAMP-dependent protein kinase type II-beta regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
[a.k.a. R-HSA-388396, R-HSA-9006925, R-HSA-69278]
7) '9606.LINC00473':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
8) '9606.ENSP00000376475':
PRKAR1A - cAMP-dependent protein kinase type I-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
[a.k.a. R-HSA-388396, EAW89065.1, ENSP00000351410]
9) '9606.ENSP00000377836':
GPC3 - Glypican-3 alpha subunit; Cell surface proteoglycan that bears heparan sulfate. Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins (By similarity). Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation (By similarity). Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligand [...]
[a.k.a. R-HSA-388396, R-HSA-196854, R-HSA-975634]
10) '9606.ENSP00000359719':
PRKACB - cAMP-dependent protein kinase catalytic subunit beta; Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subu [...]
[a.k.a. R-HSA-388396, XM_017001707.1, NP_001229790.1]
