Your Input: | |||||
CACHD1 | |||||
AVP | |||||
NPPA | |||||
BMP8A | |||||
MLN | |||||
BMP8B | |||||
REN | |||||
PTPRQ | |||||
OR4Q3 | |||||
OR1J2 |
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AVP | NPPA | ENSP00000369647 | ENSP00000365663 | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. | 0.787 |
AVP | REN | ENSP00000369647 | ENSP00000272190 | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.825 |
BMP8A | BMP8B | ENSP00000327440 | ENSP00000361915 | Bone morphogenetic protein 8A; Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT. | Bone morphogenetic protein 8B; Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity); Belongs to the TGF-beta family. | 0.903 |
BMP8B | BMP8A | ENSP00000361915 | ENSP00000327440 | Bone morphogenetic protein 8B; Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity); Belongs to the TGF-beta family. | Bone morphogenetic protein 8A; Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT. | 0.903 |
NPPA | AVP | ENSP00000365663 | ENSP00000369647 | Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | 0.787 |
NPPA | REN | ENSP00000365663 | ENSP00000272190 | Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.941 |
REN | AVP | ENSP00000272190 | ENSP00000369647 | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | 0.825 |
REN | NPPA | ENSP00000272190 | ENSP00000365663 | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. | 0.941 |