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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000252242':
KRT5 - Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family.
[a.k.a. 3852, ENSP00000449651, CCDS8830]
2) '9606.ENSP00000269571':
ERBB2 - Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]
[a.k.a. 6BGT, ENST00000582648, ENSP00000269571]
3) '9606.ENSP00000325120':
PGR - Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as transcriptional activator or repressor. [Isoform B]: Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
[a.k.a. NR3C3, NM_000926, 3G8O]
4) '9606.FNDC1-IT1':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000405330':
ESR1 - Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]
[a.k.a. AL049821, ESR1-206, 3DT3]
6) '9606.AC104088.1':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000345001':
CRTC1 - CREB-regulated transcription coactivator 1; Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved [...]
[a.k.a. NP_001091952.1, XM_005259836.3, OTTHUMG00000183115]
8) '9606.ENSP00000329243':
KRT7 - Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family.
[a.k.a. 4XIF, CK-7, URS00008BC711]
9) '9606.ENSP00000167586':
KRT14 - Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
[a.k.a. AAP35850.1, HPA023040, Q9UBN2]
10) '9606.NAALADL2-AS2':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
