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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000278836':
MYRF - Myelin regulatory factor, C-terminal; [Myelin regulatory factor]: Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes. [Myelin regulatory factor, N-terminal]: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG, DUSP15 and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifi [...]
[a.k.a. ENSP00000374254, MRF, XP_005274282]
2) '9606.ENSP00000360762':
ANKRD1 - Ankyrin repeat domain-containing protein 1; May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.
[a.k.a. AAH18667.1, ENSG00000148677, R-HSA-556833]
3) '9606.ENSP00000287538':
ZIC3 - Zinc finger protein ZIC 3; Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC- 3'; Belongs to the GLI C2H2-type zinc-finger protein family.
[a.k.a. Q14DE5, Zic family member 3, ACB30403.1]
4) '9606.ENSP00000266560':
RBP5 - Retinol-binding protein 5; Intracellular transport of retinol.
[a.k.a. NM_031491, OTTHUMG00000168165, CRBP-III]
5) '9606.ENSP00000309913':
TBX5 - T-box transcription factor TBX5; DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation. Binds to the core DNA motif of NPPA promoter.
[a.k.a. T-box transcription factor 5, NM_000192, 6910]
6) '9606.ENSP00000321856':
CRELD1 - Protein disulfide isomerase CRELD1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane (By similarity); Belongs to the CRELD family.
[a.k.a. NM_001031717.3, ENST00000451580, CCDS2593.1]
7) '9606.ENSP00000435712':
GATA4 - Transcription factor GATA-4; Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in coope [...]
[a.k.a. NP_002043.2, NP_001295022.1, GATA4-207]
8) '9606.ENSP00000327758':
NKX2-5 - Homeobox protein Nkx-2.5; Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). Binds to the core DNA motif of NPPA promoter. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development.
[a.k.a. ENSG00000183072, ENST00000329198, XM_017009071]
9) '9606.ENSP00000359871':
ACADM - Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
[a.k.a. KU177876, HPA026542, M91426]
10) '9606.CECR7':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
