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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000221992':
CEACAM5 - Carcinoembryonic antigen-related cell adhesion molecule 5; Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells. Belongs to the immunoglobulin superfamily. CEA family.
[a.k.a. R-HSA-202733, ENSP00000480800, ENST00000398599]
2) '9606.ENSP00000167588':
KRT20 - Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
[a.k.a. 54474, CCDS11379, R-HSA-6805567]
3) '9606.ENSP00000329243':
KRT7 - Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family.
[a.k.a. 4XIF, CK-7, URS00008BC711]
4) '9606.ENSP00000353245':
C17orf97 - Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation.
[a.k.a. BC057385, ENST00000339337, NM_001013672]
5) '9606.hsa-miR-4328':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000370408':
CDX2 - Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA.
[a.k.a. NM_001354700, UPI000013E4C8, CDX2_HUMAN]
7) '9606.ENSP00000256078':
KRAS - GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.
[a.k.a. R-HSA-9026519, 4L8G, 6M9W]
8) '9606.ENSP00000494061':
MUC2 - Mucin-2; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.
[a.k.a. ENST00000361558.7, ENST00000361558, MUC2-203]
9) '9606.ENSP00000269305':
TP53 - Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]
[a.k.a. NM_001126113, ENSP00000481638, R-HSA-2559584]
10) '9606.ENSP00000379138':
AFP - Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties; Belongs to the ALB/AFP/VDB family.
[a.k.a. CHEMBL3712864, NP_001125.1, 174]
