Your Input: | |||||
KRT7 | |||||
AMACR | |||||
NKX2-1 | |||||
KRT5 | |||||
KRAS | |||||
TFE3 | |||||
KRT20 | |||||
NAPSA | |||||
SFTPC | |||||
C17orf97 |
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMACR | KRT5 | ENSP00000371517 | ENSP00000252242 | Alpha-methylacyl-CoA racemase; Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2- (4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs ; Belongs to the CoA-transferase III family. | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | 0.723 |
AMACR | KRT7 | ENSP00000371517 | ENSP00000329243 | Alpha-methylacyl-CoA racemase; Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2- (4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs ; Belongs to the CoA-transferase III family. | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. | 0.811 |
C17orf97 | KRT5 | ENSP00000353245 | ENSP00000252242 | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | 0.824 |
C17orf97 | KRT7 | ENSP00000353245 | ENSP00000329243 | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. | 0.960 |
C17orf97 | NAPSA | ENSP00000353245 | ENSP00000253719 | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | Napsin-A; May be involved in processing of pneumocyte surfactant precursors. | 0.814 |
C17orf97 | NKX2-1 | ENSP00000353245 | ENSP00000346879 | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptio [...] | 0.781 |
KRT20 | NAPSA | ENSP00000167588 | ENSP00000253719 | Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). | Napsin-A; May be involved in processing of pneumocyte surfactant precursors. | 0.821 |
KRT20 | NKX2-1 | ENSP00000167588 | ENSP00000346879 | Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). | Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptio [...] | 0.841 |
KRT5 | AMACR | ENSP00000252242 | ENSP00000371517 | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | Alpha-methylacyl-CoA racemase; Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2- (4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs ; Belongs to the CoA-transferase III family. | 0.723 |
KRT5 | C17orf97 | ENSP00000252242 | ENSP00000353245 | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | 0.824 |
KRT5 | NAPSA | ENSP00000252242 | ENSP00000253719 | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | Napsin-A; May be involved in processing of pneumocyte surfactant precursors. | 0.792 |
KRT5 | NKX2-1 | ENSP00000252242 | ENSP00000346879 | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptio [...] | 0.728 |
KRT7 | AMACR | ENSP00000329243 | ENSP00000371517 | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. | Alpha-methylacyl-CoA racemase; Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2- (4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs ; Belongs to the CoA-transferase III family. | 0.811 |
KRT7 | C17orf97 | ENSP00000329243 | ENSP00000353245 | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | 0.960 |
KRT7 | NAPSA | ENSP00000329243 | ENSP00000253719 | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. | Napsin-A; May be involved in processing of pneumocyte surfactant precursors. | 0.881 |
KRT7 | NKX2-1 | ENSP00000329243 | ENSP00000346879 | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. | Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptio [...] | 0.873 |
NAPSA | C17orf97 | ENSP00000253719 | ENSP00000353245 | Napsin-A; May be involved in processing of pneumocyte surfactant precursors. | Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation. | 0.814 |
NAPSA | KRT20 | ENSP00000253719 | ENSP00000167588 | Napsin-A; May be involved in processing of pneumocyte surfactant precursors. | Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). | 0.821 |
NAPSA | KRT5 | ENSP00000253719 | ENSP00000252242 | Napsin-A; May be involved in processing of pneumocyte surfactant precursors. | Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. | 0.792 |
NAPSA | KRT7 | ENSP00000253719 | ENSP00000329243 | Napsin-A; May be involved in processing of pneumocyte surfactant precursors. | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. | 0.881 |