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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000301305':
SLC39A4 - Zinc transporter ZIP4; Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability (By similarity).
[a.k.a. OTTHUMG00000165208, Zrt- and Irt-like protein 4, R-HSA-425410]
2) '9606.ENSP00000259212':
IL36RN - Interleukin-36 receptor antagonist protein; Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti- inflammatory s [...]
[a.k.a. FIL1D, ENSP00000259212, PSORS14]
3) '9606.ENSP00000323527':
MKLN1 - Muskelin; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Required for internalization of the GABA receptor GABRA1 from the cell membrane via endosomes and subsequent GABRA1 degradation (By similarity). Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component THBS1.
[a.k.a. ENST00000355381, ENST00000494785, XP_011514526]
4) '9606.ENSP00000228251':
YBX3 - Y-box-binding protein 3; Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full-length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity).
[a.k.a. XM_017020123, L29064, ENST00000366290]
5) '9606.ENSP00000420174':
ERVFRD-1 - Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process.
[a.k.a. AK123938, NP_997465, Transmembrane protein]
6) '9606.ENSP00000391594':
ERV3-1 - Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediate [...]
[a.k.a. Endogenous retrovirus group 3 member 1, envelope, Transmembrane protein, ENST00000528878]
7) '9606.ENSP00000379891':
AP1S3 - AP-1 complex subunit sigma-3; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking.
[a.k.a. ENSP00000281839, PSORS15, NX_Q96PC3]
8) '9606.ENSP00000498071':
CARD14 - Caspase recruitment domain-containing protein 14; Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases. May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis.
[a.k.a. XP_024306703, ENSG00000141527, UPI000013D81B]
9) '9606.ENSP00000419945':
ERVW-1 - Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5.
[a.k.a. AF208161, envW, 30816]
10) '9606.SNORA1':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
