Your Input: | |||||
DAZ1 | |||||
USP9Y | |||||
AMH | |||||
DAZ3 | |||||
PRM2 | |||||
DAZ2 | |||||
DAZL | |||||
HSFY1 | |||||
TSSK6 | |||||
BPY2B |
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BPY2B | DAZ1 | ENSP00000371829 | ENSP00000384573 | Basic charge Y-linked 2B. | Deleted in azoospermia protein 1; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells. | 0.932 |
BPY2B | DAZ2 | ENSP00000371829 | ENSP00000371870 | Basic charge Y-linked 2B. | Deleted in azoospermia 2. | 0.898 |
BPY2B | DAZ3 | ENSP00000371829 | ENSP00000371802 | Basic charge Y-linked 2B. | Deleted in azoospermia protein 2; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. | 0.881 |
BPY2B | HSFY1 | ENSP00000371829 | ENSP00000303599 | Basic charge Y-linked 2B. | Heat shock transcription factor Y-linked 1; Belongs to the HSF family. | 0.760 |
BPY2B | USP9Y | ENSP00000371829 | ENSP00000342812 | Basic charge Y-linked 2B. | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...] | 0.840 |
DAZ1 | BPY2B | ENSP00000384573 | ENSP00000371829 | Deleted in azoospermia protein 1; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells. | Basic charge Y-linked 2B. | 0.932 |
DAZ1 | DAZ2 | ENSP00000384573 | ENSP00000371870 | Deleted in azoospermia protein 1; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells. | Deleted in azoospermia 2. | 0.999 |
DAZ1 | HSFY1 | ENSP00000384573 | ENSP00000303599 | Deleted in azoospermia protein 1; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells. | Heat shock transcription factor Y-linked 1; Belongs to the HSF family. | 0.709 |
DAZ1 | USP9Y | ENSP00000384573 | ENSP00000342812 | Deleted in azoospermia protein 1; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells. | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...] | 0.884 |
DAZ2 | BPY2B | ENSP00000371870 | ENSP00000371829 | Deleted in azoospermia 2. | Basic charge Y-linked 2B. | 0.898 |
DAZ2 | DAZ1 | ENSP00000371870 | ENSP00000384573 | Deleted in azoospermia 2. | Deleted in azoospermia protein 1; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells. | 0.999 |
DAZ2 | USP9Y | ENSP00000371870 | ENSP00000342812 | Deleted in azoospermia 2. | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...] | 0.780 |
DAZ3 | BPY2B | ENSP00000371802 | ENSP00000371829 | Deleted in azoospermia protein 2; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. | Basic charge Y-linked 2B. | 0.881 |
DAZ3 | USP9Y | ENSP00000371802 | ENSP00000342812 | Deleted in azoospermia protein 2; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...] | 0.758 |
HSFY1 | BPY2B | ENSP00000303599 | ENSP00000371829 | Heat shock transcription factor Y-linked 1; Belongs to the HSF family. | Basic charge Y-linked 2B. | 0.760 |
HSFY1 | DAZ1 | ENSP00000303599 | ENSP00000384573 | Heat shock transcription factor Y-linked 1; Belongs to the HSF family. | Deleted in azoospermia protein 1; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells. | 0.709 |
USP9Y | BPY2B | ENSP00000342812 | ENSP00000371829 | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...] | Basic charge Y-linked 2B. | 0.840 |
USP9Y | DAZ1 | ENSP00000342812 | ENSP00000384573 | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...] | Deleted in azoospermia protein 1; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells. | 0.884 |
USP9Y | DAZ2 | ENSP00000342812 | ENSP00000371870 | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...] | Deleted in azoospermia 2. | 0.780 |
USP9Y | DAZ3 | ENSP00000342812 | ENSP00000371802 | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...] | Deleted in azoospermia protein 2; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. | 0.758 |