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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000441235':
TSHR - Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism (By similarity); Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
[a.k.a. ENST00000636454, R-HSA-388396, XM_005268039.1]
2) '9606.ENSP00000303356':
DCXR - L-xylulose reductase; Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
[a.k.a. ENST00000584318.1, ENST00000577996.1, HPA023371]
3) '9606.ENSP00000478561':
CYP1B1 - Cytochrome P450 1B1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Exhibits catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2- and 4-hydroxy E1 and E2. Displays a predominant hydroxylase activity towar [...]
[a.k.a. Q16678, R-HSA-2142670, CYP1B1-201]
4) '9606.ENSP00000261978':
LTBP2 - Latent-transforming growth factor beta-binding protein 2; May play an integral structural role in elastic-fiber architectural organization and/or assembly. Belongs to the LTBP family.
[a.k.a. R-HSA-2129379, ENST00000329329, NP_000419]
5) '9606.ENSP00000037502':
MYOC - Myocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. [...]
[a.k.a. 4WXU, GLC1A, Myocilin, C-terminal fragment]
6) '9606.ENSP00000257867':
LACRT - Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells.
[a.k.a. ENST00000257867, Q9GZZ8, NM_033277]
7) '9606.ENSP00000423067':
WDR36 - WD repeat-containing protein 36; Involved in the nucleolar processing of SSU 18S rRNA. Involved in T-cell activation and highly coregulated with IL2.
[a.k.a. TA-WDRP, ENST00000506538.6, 134430]
8) '9606.ENSP00000231751':
LTF - Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin binds to the bacterial surface and is crucial for the bactericidal functions. Has some antiviral activity against papillomavirus infection. N-terminal region shows strong antifungal activity against C.albicans. Contains two BBXB heparin-binding consensus sequences that appear to form the predominate functional GAG- binding site. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows pr [...]
[a.k.a. ENST00000478874.2, 2BJJ, Growth-inhibiting protein 12]
9) '9606.hsa-miR-7152-3p':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000263598':
LCN1 - Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family.
[a.k.a. R-HSA-804914, 3EYC, ENSP00000263598]
