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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000451040':
PGF - Placenta growth factor; Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
[a.k.a. P49763, R-HSA-162582, 1RV6]
2) '9606.ENSP00000330658':
PAPPA - Pappalysin-1; Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF. Belongs to the peptidase M43B family.
[a.k.a. uc004bjn.4, 3.4.24.79, DIPLA1]
3) '9606.SNORA108':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
4) '9606.ENSP00000362299':
ENG - Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a critical role in the binding of endothelial cells to integrins [...]
[a.k.a. CHEMBL3712885, EAW87703.1, LRG_589t2]
5) '9606.ENSP00000272190':
REN - Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
[a.k.a. 4GJA, ENSP00000272190, Angiotensinogenase]
6) '9606.ENSP00000282397':
FLT1 - Vascular endothelial growth factor receptor 1; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferati [...]
[a.k.a. ENSP00000443311, ACF47597.1, 4CL7]
7) '9606.ENSP00000490038':
RAB6D - Ras-related protein Rab-6D; RAB6D, member RAS oncogene family; Belongs to the small GTPase superfamily. Rab family.
[a.k.a. 150786, RAB6D, member RAS oncogene family, NM_001077637.1]
8) '9606.ENSP00000263776':
ACCS - 1-aminocyclopropane-1-carboxylate synthase-like protein 1; Does not catalyze the synthesis of 1-aminocyclopropane-1- carboxylate but is capable of catalyzing the deamination of L- vinylglycine.
[a.k.a. XP_011518709, ENST00000527557.5, ENST00000524990.5]
9) '9606.ENSP00000363117':
FGR - Tyrosine-protein kinase Fgr; Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors devoid of kinase activity and contributes to the regulation of immune responses, including neutrophil, monocyte, macrophage and mast cell functions, cytoskeleton remodeling in response to extracellular stimuli, phagocytosis, cell adhesion and migration. Promotes mast cell degranulation, release of inflammatory cytokines and IgE-mediated anaphylaxis. Acts downstream of receptors that bind the Fc region of immunoglobulins, such as MS4A2/FCER1B, FCGR2A and/or FCGR2B. Acts d [...]
[a.k.a. 2.7.10.2, ENST00000374005.7, XM_011541011.2]
10) '9606.hsa-miR-6757-5p':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
