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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000395535':
MECP2 - Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).
[a.k.a. XM_011531166, MRXSL, MECP2-224]
2) '9606.ENSP00000489407':
SHANK3 - SH3 and multiple ankyrin repeat domains protein 3; Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex [...]
[a.k.a. ENST00000445220.5, NP_001358973.1, NM_033517.1]
3) '9606.ENSP00000370483':
NLGN4X - Neuroligin-4, X-linked; Putative neuronal cell surface protein involved in cell-cell- interactions; Belongs to the type-B carboxylesterase/lipase family.
[a.k.a. XP_016885182.1, XM_017029693.1, XM_005274565]
4) '9606.ENSP00000351591':
NLGN3 - Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity); Belongs to the type-B carboxylesterase/lipase family.
[a.k.a. NLGN3-203, Neuroligin, BC051715]
5) '9606.ENSP00000354778':
CNTNAP2 - Contactin-associated protein-like 2; Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction.
[a.k.a. ENST00000636600.1, CR933671, NM_014141.6]
6) '9606.ENSP00000385142':
NRXN1 - Neurexin-1; Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N- terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect [...]
[a.k.a. CCDS82449.1, UPI0005C1219A, AC007680]
7) '9606.RNU105B':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
8) '9606.ENSP00000345193':
SHANK2 - SH3 and multiple ankyrin repeat domains protein 2; Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
[a.k.a. NP_036441.2, ENST00000357171.7, PROSAP1]
9) '9606.ENSP00000231021':
CDH9 - Cadherin-9; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
[a.k.a. ENST00000505045.1, Cadherin 9, NM_016279]
10) '9606.ENSP00000217386':
OXT - Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin.
[a.k.a. R-HSA-388396, Oxytocin/neurophysin I prepropeptide, AAA59979.1]