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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000234347':
PRTN3 - Myeloblastin; Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177. Belongs to the peptidase S1 family. Elastase subfamily.
[a.k.a. OMIM:177020, X56132, C-ANCA]
2) '9606.ENSP00000255030':
CRP - C-reactive protein(1-205); Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
[a.k.a. R-HSA-173623, CCDS30911, CRP-207]
3) '9606.ENSP00000290866':
ACE - Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety; Belongs to the peptidase M2 family.
[a.k.a. ENST00000582005.5, 4BZS, ENST00000577418]
4) '9606.ENSP00000364298':
FKBPL - FK506-binding protein-like; May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.
[a.k.a. AL662884, R-HSA-69278, FKBP4]
5) '9606.CASC21':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000322924':
HTR1F - 5-hydroxytryptamine receptor 1F; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
[a.k.a. R-HSA-388396, 5-HT1F, R-HSA-162582]
7) '9606.ENSP00000366091':
MOG - Myelin-oligodendrocyte glycoprotein; Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Belongs to the immunoglobulin superfamily. BTN/MOG family.
[a.k.a. MOG-232, ENSP00000366095, MOG-220]
8) '9606.ENSP00000363571':
MUSK - Muscle, skeletal receptor tyrosine-protein kinase; Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskel [...]
[a.k.a. HGNC:7525, CCDS48005.1, ENSP00000363563]
9) '9606.ENSP00000395281':
C9orf116 - UPF0691 protein C9orf116; Chromosome 9 open reading frame 116.
[a.k.a. ENST00000530499, ENST00000429260.6, ENST00000429260]
10) '9606.ENSP00000325548':
CNDP2 - Cytosolic non-specific dipeptidase; Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation. Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Catalyzes the production of N-lactoyl-amino acids from lactate [...]
[a.k.a. ENSP00000462034, J3QRD0, ENST00000584581]
