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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000263388':
NOTCH3 - Neurogenic locus notch homolog protein 3; Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).
[a.k.a. NX_Q9UM47, R-HSA-162582, R-HSA-1912399]
2) '9606.ENSP00000482753':
C9orf72 - Guanine nucleotide exchange C9orf72; Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP- bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and modulating its protein kinase activity. Positivel [...]
[a.k.a. NP_659442.2, MGC23980, 203228]
3) '9606.ENSP00000240185':
TARDBP - TAR DNA-binding protein 43; RNA-binding protein that is involved in various steps of RNA biogenesis and processing. Preferentially binds, via its two RNA recognition motifs RRM1 and RRM2, to GU-repeats on RNA molecules predominantly localized within long introns and in the 3'UTR of mRNAs. In turn, regulates the splicing of many non-coding and protein-coding RNAs including proteins involved in neuronal survival, as well as mRNAs that encode proteins relevant for neurodegenerative diseases. Plays a role in maintaining mitochondrial homeostasis by regulating the processing of mitochondria [...]
[a.k.a. ENSP00000467020, XM_017000868, ENST00000240185]
4) '9606.ENSP00000481594':
OR56A5 - Olfactory receptor 56A5; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
[a.k.a. R-HSA-388396, UPI0000D625A7, R-HSA-162582]
5) '9606.ENSP00000330338':
OR52L1 - Olfactory receptor 52L1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
[a.k.a. R-HSA-388396, R-HSA-162582, ENSP00000330338]
6) '9606.hsa-miR-6840-5p':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000485527':
CBSL - Cystathionine beta-synthase like.
[a.k.a. NM_001354015, UPI0000169740, NP_001340937.1]
8) '9606.ENSP00000381231':
CBS - Cystathionine beta-synthase-like protein; Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.
[a.k.a. CBS-213, CBS-201, XP_016883979.1]
9) '9606.ENSP00000445725':
RNF170 - E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells.
[a.k.a. ENST00000524954, BC013422, RNF170-208]
10) '9606.ENSP00000270142':
SOD1 - Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.
[a.k.a. 3GTV, 1HL4, A6NHJ0]