Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
payload active
DISEASES
The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
<- Back
⤓ Mapping
Continue ->
1) '9606.ENSP00000261707':
SLC6A4 - Sodium-dependent serotonin transporter; Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
[a.k.a. CCDS11256, NM_001045, ENST00000394821]
2) '9606.ENSP00000362444':
DLGAP3 - Disks large-associated protein 3; May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD- 95/SAP90 at the plasma membrane; Belongs to the SAPAP family.
[a.k.a. Q5TDD5, URS00008C32CC, OTTHUMG00000004049]
3) '9606.ENSP00000354859':
DRD2 - D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family.
[a.k.a. ENST00000355319, AF176812, R-HSA-162582]
4) '9606.ENSP00000316244':
HTR1A - 5-hydroxytryptamine receptor 1A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second [...]
[a.k.a. R-HSA-388396, CAA40962.1, R-HSA-162582]
5) '9606.ENSP00000306678':
ANKK1 - Ankyrin repeat and kinase domain containing 1.
[a.k.a. NM_178510.1, NM_178510, CHEMBL5547]
6) '9606.ENSP00000354511':
COMT - Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
[a.k.a. ENSP00000385150, uc002zqu.4, 4XUC]
7) '9606.ENSP00000299314':
GNPTAB - N-acetylglucosamine-1-phosphotransferase subunits alpha/beta; Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment.
[a.k.a. ENST00000647144, ENSP00000308378, ENST00000299314.11]
8) '9606.ENSP00000270349':
SLC6A3 - Sodium-dependent dopamine transporter; Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
[a.k.a. DAT1, AF306563, AAA35770.1]
9) '9606.ENSP00000340684':
MAOA - Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
[a.k.a. OTTHUMG00000021387, ENSP00000340684, EC 1.4.3.4]
10) '9606.SNORD116':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -