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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000380008':
LTB4R - Leukotriene B4 receptor 1; Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response; Belongs to the G-protein coupled receptor 1 family.
[a.k.a. R-HSA-388396, GPR16, BT007267]
2) '9606.ENSP00000432651':
SMTNL1 - Smoothelin-like protein 1; Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity).
[a.k.a. ENSP00000406485, XM_005273819.3, ENST00000399154]
3) '9606.ENSP00000257867':
LACRT - Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells.
[a.k.a. ENST00000257867, Q9GZZ8, NM_033277]
4) '9606.ENSP00000361405':
MMP9 - 67 kDa matrix metalloproteinase-9; May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Belongs to the peptidase M10A family.
[a.k.a. AAA51539.1, Matrix metallopeptidase 9, 4WZV]
5) '9606.ENSP00000341108':
HMX2 - Homeobox protein HMX2; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development; Belongs to the HMX homeobox family.
[a.k.a. CAB013268, H6 family homeobox 2, CAB022752]
6) '9606.ENSP00000307959':
DST - Dystonin; Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Mediates docking of the dynein/dynactin motor complex to vesicle cargos for re [...]
[a.k.a. ENST00000517840, DST-235, UPI0000470A23]
7) '9606.ENSP00000413479':
KRT3 - Keratin, type II cytoskeletal 3; Keratin 3; Belongs to the intermediate filament family.
[a.k.a. ENST00000417996, XM_024448975, K2C3_HUMAN]
8) '9606.ENSP00000263598':
LCN1 - Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family.
[a.k.a. R-HSA-804914, 3EYC, ENSP00000263598]
9) '9606.NHS-AS1':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000231751':
LTF - Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin binds to the bacterial surface and is crucial for the bactericidal functions. Has some antiviral activity against papillomavirus infection. N-terminal region shows strong antifungal activity against C.albicans. Contains two BBXB heparin-binding consensus sequences that appear to form the predominate functional GAG- binding site. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows pr [...]
[a.k.a. ENST00000478874.2, 2BJJ, Growth-inhibiting protein 12]
