Your Input: | |||||
AVP | |||||
NPTX2 | |||||
AQP2 | |||||
AVPR2 | |||||
OXT | |||||
POMC | |||||
AVPR1B | |||||
AVPR1A | |||||
AGT | |||||
UBOX5 |
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGT | AVP | ENSP00000355627 | ENSP00000369647 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | 0.837 |
AGT | AVPR1A | ENSP00000355627 | ENSP00000299178 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.829 |
AGT | AVPR1B | ENSP00000355627 | ENSP00000356094 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.725 |
AGT | AVPR2 | ENSP00000355627 | ENSP00000496396 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. | Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.800 |
AGT | OXT | ENSP00000355627 | ENSP00000217386 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. | Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin. | 0.785 |
AGT | POMC | ENSP00000355627 | ENSP00000384092 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. | Corticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Melanocyte-stimulating hormone beta]: Increases the pigmentation of skin by increasing melanin production in melanocytes. [Met-enkephalin]: Endogenous opiate; Belongs to the POMC family. | 0.887 |
AQP2 | AVP | ENSP00000199280 | ENSP00000369647 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis. | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | 0.915 |
AQP2 | AVPR2 | ENSP00000199280 | ENSP00000496396 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis. | Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.982 |
AVP | AGT | ENSP00000369647 | ENSP00000355627 | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. | 0.837 |
AVP | AQP2 | ENSP00000369647 | ENSP00000199280 | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis. | 0.915 |
AVP | AVPR1A | ENSP00000369647 | ENSP00000299178 | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.999 |
AVP | AVPR1B | ENSP00000369647 | ENSP00000356094 | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.995 |
AVP | AVPR2 | ENSP00000369647 | ENSP00000496396 | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.999 |
AVP | NPTX2 | ENSP00000369647 | ENSP00000265634 | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | Neuronal pentraxin-2; Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity). | 0.833 |
AVP | OXT | ENSP00000369647 | ENSP00000217386 | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin. | 0.959 |
AVP | POMC | ENSP00000369647 | ENSP00000384092 | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | Corticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Melanocyte-stimulating hormone beta]: Increases the pigmentation of skin by increasing melanin production in melanocytes. [Met-enkephalin]: Endogenous opiate; Belongs to the POMC family. | 0.879 |
AVPR1A | AGT | ENSP00000299178 | ENSP00000355627 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. | 0.829 |
AVPR1A | AVP | ENSP00000299178 | ENSP00000369647 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin. | 0.999 |
AVPR1A | AVPR1B | ENSP00000299178 | ENSP00000356094 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.940 |
AVPR1A | AVPR2 | ENSP00000299178 | ENSP00000496396 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.953 |