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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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⤓ Mapping
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1) '9606.ENSP00000249389':
OPN1SW - Short-wave-sensitive opsin 1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (Probable). Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors (By similarity). Involved in ensuring correct abundance and localization of retinal membrane proteins (By similarity). May increase spectral sensitivity in dim light (By similarity); Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
[a.k.a. R-HSA-388396, M13295, 611]
2) '9606.ENSP00000360502':
PDE6C - Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP.
[a.k.a. NX_P51160, U20206, Q5VY29]
3) '9606.ENSP00000266395':
PDE6H - Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones; Belongs to the rod/cone cGMP-PDE gamma subunit family.
[a.k.a. RCD3, ENSP00000266395, ENST00000266395]
4) '9606.ENSP00000251337':
GNAT2 - Guanine nucleotide-binding protein G(t) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP- phosphodiesterase.
[a.k.a. R-HSA-388396, hsa:2780, 2780]
5) '9606.ENSP00000316605':
CNGB3 - Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked ele [...]
[a.k.a. Cyclic nucleotide gated channel beta 3, ENSP00000316605, ENST00000519777]
6) '9606.CTD-3032H12.2':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000472316':
OPN1MW - Opsin 1, medium wave sensitive.
[a.k.a. R-HSA-388396, color blindness, deutan, R-HSA-162582]
8) '9606.ENSP00000361141':
OPN4 - Melanopsin; Photoreceptor required for regulation of circadian rhythm. Contributes to pupillar reflex and other non-image forming responses to light. May be able to isomerize covalently bound all-trans retinal back to 11-cis retinal (By similarity); Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
[a.k.a. R-HSA-388396, ENST00000241891, NM_001030015]
9) '9606.ENSP00000272602':
CNGA3 - Cyclic nucleotide-gated cation channel alpha-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evok [...]
[a.k.a. AF065314, URS00008BDCBE, ENST00000393503.2]
10) '9606.ENSP00000319817':
OPA3 - Outer mitochondrial membrane lipid metabolism regulator OPA3.
[a.k.a. ENSP00000263275, NM_001017989, Q9H6K4]
