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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000427802':
NACA2 - Nascent polypeptide-associated complex subunit alpha-2; Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).
[a.k.a. NM_199290, BC062710, Q9H009]
2) '9606.ENSP00000359469':
ZNF644 - Zinc finger protein 644; May be involved in transcriptional regulation.
[a.k.a. URS00008C13D8, Q9H582, NM_016620]
3) '9606.ENSP00000359319':
PAX2 - Paired box protein Pax-2; Transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.
[a.k.a. M89470, ENST00000370296, ENST00000483202.2]
4) '9606.hsa_circ_001489':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000266980':
SLC39A5 - Zinc transporter ZIP5; May play a role in polarized cells by carrying out serosal- to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera. Seems to play a central role in controlling organismal zinc status (By similarity).
[a.k.a. HGNC:20502, NP_001128667.1, R-HSA-425410]
6) '9606.ENSP00000484669':
CPSF1 - Cleavage and polyadenylation specificity factor subunit 1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
[a.k.a. CPSF1-208, HGNC:2324, 6BM0]
7) '9606.ENSP00000420860':
PRIMPOL - DNA-directed primase/polymerase protein; DNA primase and DNA polymerase required to tolerate replication-stalling lesions by bypassing them. Required to facilitate mitochondrial and nuclear replication fork progression by initiating de novo DNA synthesis using dNTPs and acting as an error-prone DNA polymerase able to bypass certain DNA lesions. Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. Provides different translesion synthesis alternatives when DNA replication is stalled: able to synthesize DNA primers downstream of lesions, such as ultr [...]
[a.k.a. NP_001287697.1, Primase and DNA directed polymerase, 201973]
8) '9606.ENSP00000358967':
OPN1LW - Long-wave-sensitive opsin 1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.
[a.k.a. R-HSA-388396, R-HSA-162582, Long-wave-sensitive opsin 1]
9) '9606.ENSP00000311538':
ARR3 - Arrestin-C; May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins.
[a.k.a. ENSP00000363619, OMIM:301770, AF076511]
10) '9606.ENSP00000380165':
ZNF182 - Zinc finger protein 182; May be involved in transcriptional regulation.
[a.k.a. NM_006962.1, ZNF182-201, NM_006962]
