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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000413001':
AGBL1 - Cytosolic carboxypeptidase 4; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
[a.k.a. Cytosolic carboxypeptidase protein 4, Q96MI9, AC016180]
2) '9606.ENSP00000369399':
SLC4A11 - Sodium bicarbonate transporter-like protein 11; Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into th [...]
[a.k.a. BAG59140.1, XP_016883582.1, BTR1]
3) '9606.ENSP00000360195':
KANK4 - KN motif and ankyrin repeat domain-containing protein 4; May be involved in the control of cytoskeleton formation by regulating actin polymerization.
[a.k.a. AL162739, B1ALP7, B1ALP6]
4) '9606.ENSP00000380901':
COL8A2 - Collagen alpha-2(VIII) chain; Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity).
[a.k.a. NP_005193.1, R-HSA-8948216, collagen type VIII alpha 2]
5) '9606.ENSP00000381382':
TCF4 - Transcription factor 4; Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'- CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'- CCANNTGG-3'.
[a.k.a. ENST00000564999, BAG52974.1, NP_001230163.1]
6) '9606.ENSP00000258341':
LAMC1 - Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
[a.k.a. uc001gpy.4, R-HSA-6806834, M55198]
7) '9606.ENSP00000354487':
ZEB1 - Zinc finger E-box-binding homeobox 1; Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG [...]
[a.k.a. ENSP00000453970, NM_001323642.2, NP_001310570.1]
8) '9606.ENSP00000356790':
ATP1B1 - Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
[a.k.a. R-HSA-202733, UPI0000126296, ATP1B]
9) '9606.ENSP00000444586':
LOXHD1 - Lipoxygenase homology domain-containing protein 1; Involved in hearing. Required for normal function of hair cells in the inner ear (By similarity).
[a.k.a. B7WPI9, ENSP00000381707, ENSP00000414278]
10) '9606.LINC00970':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
