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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000334472':
FOXE3 - Forkhead box protein E3; Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle. During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (By similarity). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (By similarity). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye.
[a.k.a. AL607122, AIY30327.1, ENST00000335071]
2) '9606.ENSP00000492024':
PAX6 - Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes; Belongs to the paired homeobox family.
[a.k.a. ENST00000524853, hsa:5080, ENSG00000007372]
3) '9606.ENSP00000358238':
GJA8 - Gap junction alpha-8 protein; Structural component of eye lens gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity). Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
[a.k.a. Gap junction protein alpha 8, NX_P48165, OTTHUMG00000024085]
4) '9606.ENSP00000498905':
CRYBB2 - Beta-crystallin B2; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family.
[a.k.a. KR052784, Crystallin beta B2, U72401]
5) '9606.ENSP00000363417':
SLC7A3 - Cationic amino acid transporter 3; Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
[a.k.a. R-HSA-352230, CAT-3, hsa:84889]
6) '9606.CECR7':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000343002':
B3GLCT - Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.
[a.k.a. HGNC:20207, NP_919299.3, ENSP00000343002]
8) '9606.ENSP00000260988':
CRYGB - Gamma-crystallin B; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family.
[a.k.a. 1MZ1, 2JDG, crystallin gamma B]
9) '9606.ENSP00000370139':
HCCS - Cytochrome c-type heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
[a.k.a. 4.4.1.17, ENST00000321143.8, ENSP00000370144]
10) '9606.ENSP00000359665':
PI4K2A - Phosphatidylinositol 4-kinase type 2-alpha; Membrane-bound phosphatidylinositol-4 kinase (PI4-kinase) that catalyzes the phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P), a lipid that plays important roles in endocytosis, Golgi function, protein sorting and membrane trafficking and is required for prolonged survival of neurons. Besides, phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4- phosphate (PI4P) is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second mess [...]
[a.k.a. 55361, Q9NSG8, ENSG00000155252]
