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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000453502':
ST20 - Suppressor of tumorigenicity 20 protein; May act as a tumor suppressor. Promotes apoptosis of cancer cells.
[a.k.a. ENSP00000453502, NP_001094350.1, AF249277]
2) '9606.ENSP00000425261':
COX18 - Cytochrome c oxidase assembly protein COX18, mitochondrial; Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT- CO2/COX2) across the mitochondrial inner membrane. Plays a role in MT- CO2/COX2 maturation following the COX20-mediated stabilization of newly synthesized MT-CO2/COX2 protein and before the action of the metallochaperones SCO1/2. Essential for the assembly and stability of the mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase); Belongs to the OXA1/ALB3/YidC family.
[a.k.a. AAY35061.1, AY957565, HPA049489]
3) '9606.ENSP00000304376':
RAB24 - Ras-related protein Rab-24; May be involved in autophagy-related processes. Belongs to the small GTPase superfamily. Rab family.
[a.k.a. ENST00000478234.5, UPI000013315F, ENST00000303270]
4) '9606.ENSP00000255030':
CRP - C-reactive protein(1-205); Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
[a.k.a. R-HSA-173623, CCDS30911, CRP-207]
5) '9606.ENSP00000229135':
IFNG - Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.
[a.k.a. ENSG00000111537, IFNG-201, NM_000619]
6) '9606.ENSP00000340019':
HSPD1 - 60 kDa heat shock protein, mitochondrial; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back- to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ri [...]
[a.k.a. SPG13, ENSP00000441296, HSPD1-208]
7) '9606.CTC-455F18.1':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
8) '9606.ENSP00000412237':
IL10 - Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro- inflammatory cytokines i [...]
[a.k.a. uc001hen.2, ENST00000664374, ENSP00000499664]
9) '9606.ENSP00000273047':
RAB5A - Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...]
[a.k.a. 1R2Q, CAB004567, ENSG00000144566]
10) '9606.ENSP00000333298':
LAMP1 - Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
[a.k.a. Lysosome-associated membrane glycoprotein 1, BC007845, CCDS41909.1]
