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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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⤓ Mapping
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1) '9606.ENSP00000443168':
STH - Saitohin.
[a.k.a. uc002ijy.2, NM_001007532.2, AAO03577.1]
2) '9606.ENSP00000011653':
CD4 - T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]
[a.k.a. R-HSA-162587, 3JCC, 4Q6I]
3) '9606.ENSP00000231454':
IL5 - Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells; Belongs to the IL-5 family.
[a.k.a. R-HSA-912526, IL5-202, XM_011543373.2]
4) '9606.18S_rRNA':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000354499':
MT-CO1 - Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]
[a.k.a. COX1, KY409861, KJ446191]
6) '9606.ENSP00000231449':
IL4 - Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages (By similarity). Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4 (By [...]
[a.k.a. BC066277, NX_P05112, BC070123]
7) '9606.ENSP00000304915':
IL13 - Interleukin-13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
[a.k.a. ENST00000304506.7, NM_001354992, R-HSA-446652]
8) '9606.ENSP00000412237':
IL10 - Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro- inflammatory cytokines i [...]
[a.k.a. uc001hen.2, ENST00000664374, ENSP00000499664]
9) '9606.ENSP00000252951':
HBZ - Hemoglobin subunit zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin.
[a.k.a. Z84721, Zeta-globin, hemoglobin subunit zeta]
10) '9606.ENSP00000310723':
DDX23 - Probable ATP-dependent RNA helicase DDX23; Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation.
[a.k.a. F8W1J5, 6AH0, R-HSA-72203]
