Your Input: | |||||
ASPG | |||||
NCAM1 | |||||
ACBD3 | |||||
CCDC39 | |||||
CYP27A1 | |||||
ARX | |||||
GEN1 | |||||
BCL6 | |||||
CD5 | |||||
CD2 |
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCL6 | CD5 | ENSP00000384371 | ENSP00000342681 | B-cell lymphoma 6 protein; Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors. In GC B-cells, represses gene [...] | T-cell surface glycoprotein CD5; May act as a receptor in regulating T-cell proliferation. | 0.863 |
CD2 | CD5 | ENSP00000358490 | ENSP00000342681 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | T-cell surface glycoprotein CD5; May act as a receptor in regulating T-cell proliferation. | 0.994 |
CD2 | NCAM1 | ENSP00000358490 | ENSP00000480132 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | Neural cell adhesion molecule 1; This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. | 0.921 |
CD5 | BCL6 | ENSP00000342681 | ENSP00000384371 | T-cell surface glycoprotein CD5; May act as a receptor in regulating T-cell proliferation. | B-cell lymphoma 6 protein; Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors. In GC B-cells, represses gene [...] | 0.863 |
CD5 | CD2 | ENSP00000342681 | ENSP00000358490 | T-cell surface glycoprotein CD5; May act as a receptor in regulating T-cell proliferation. | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | 0.994 |
CD5 | NCAM1 | ENSP00000342681 | ENSP00000480132 | T-cell surface glycoprotein CD5; May act as a receptor in regulating T-cell proliferation. | Neural cell adhesion molecule 1; This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. | 0.848 |
NCAM1 | CD2 | ENSP00000480132 | ENSP00000358490 | Neural cell adhesion molecule 1; This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | 0.921 |
NCAM1 | CD5 | ENSP00000480132 | ENSP00000342681 | Neural cell adhesion molecule 1; This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. | T-cell surface glycoprotein CD5; May act as a receptor in regulating T-cell proliferation. | 0.848 |