Your Input: | |||||
PRSS1 | |||||
CELA1 | |||||
SCT | |||||
PNLIP | |||||
CTRB2 | |||||
CTRB1 | |||||
CELA3B | |||||
CLPS | |||||
SPINK1 | |||||
LIPF |
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CELA3B | CTRB1 | ENSP00000338369 | ENSP00000354294 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | 0.795 |
CLPS | CTRB1 | ENSP00000259938 | ENSP00000354294 | Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | 0.801 |
CLPS | CTRB2 | ENSP00000259938 | ENSP00000303963 | Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. | Chymotrypsinogen B2; Belongs to the peptidase S1 family. | 0.932 |
CLPS | LIPF | ENSP00000259938 | ENSP00000377900 | Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. | Lipase F, gastric type. | 0.945 |
CLPS | PNLIP | ENSP00000259938 | ENSP00000358223 | Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. | Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.999 |
CTRB1 | CELA3B | ENSP00000354294 | ENSP00000338369 | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | 0.795 |
CTRB1 | CLPS | ENSP00000354294 | ENSP00000259938 | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. | 0.801 |
CTRB1 | CTRB2 | ENSP00000354294 | ENSP00000303963 | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | Chymotrypsinogen B2; Belongs to the peptidase S1 family. | 0.949 |
CTRB1 | PNLIP | ENSP00000354294 | ENSP00000358223 | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.925 |
CTRB1 | PRSS1 | ENSP00000354294 | ENSP00000308720 | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | Alpha-trypsin chain 1; Has activity against the synthetic substrates Boc-Phe-Ser- Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg- Mec. The single-chain form is more active than the two-chain form against all of these substrates; Belongs to the peptidase S1 family. | 0.863 |
CTRB1 | SPINK1 | ENSP00000354294 | ENSP00000296695 | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). | 0.885 |
CTRB2 | CLPS | ENSP00000303963 | ENSP00000259938 | Chymotrypsinogen B2; Belongs to the peptidase S1 family. | Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. | 0.932 |
CTRB2 | CTRB1 | ENSP00000303963 | ENSP00000354294 | Chymotrypsinogen B2; Belongs to the peptidase S1 family. | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | 0.949 |
CTRB2 | PNLIP | ENSP00000303963 | ENSP00000358223 | Chymotrypsinogen B2; Belongs to the peptidase S1 family. | Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.856 |
CTRB2 | PRSS1 | ENSP00000303963 | ENSP00000308720 | Chymotrypsinogen B2; Belongs to the peptidase S1 family. | Alpha-trypsin chain 1; Has activity against the synthetic substrates Boc-Phe-Ser- Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg- Mec. The single-chain form is more active than the two-chain form against all of these substrates; Belongs to the peptidase S1 family. | 0.859 |
CTRB2 | SPINK1 | ENSP00000303963 | ENSP00000296695 | Chymotrypsinogen B2; Belongs to the peptidase S1 family. | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). | 0.886 |
LIPF | CLPS | ENSP00000377900 | ENSP00000259938 | Lipase F, gastric type. | Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. | 0.945 |
LIPF | PNLIP | ENSP00000377900 | ENSP00000358223 | Lipase F, gastric type. | Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.998 |
PNLIP | CLPS | ENSP00000358223 | ENSP00000259938 | Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family. | Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. | 0.999 |
PNLIP | CTRB1 | ENSP00000358223 | ENSP00000354294 | Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family. | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | 0.925 |