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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000410715':
SFRP4 - Secreted frizzled-related protein 4; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
[a.k.a. NP_003005.2, Secreted frizzled related protein 4, AAH47684.1]
2) '9606.ENSP00000327368':
COL10A1 - Collagen alpha-1(X) chain; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.
[a.k.a. X65120, ENST00000327673, R-HSA-8948216]
3) '9606.ENSP00000402723':
PTH1R - Parathyroid hormone/parathyroid hormone-related peptide receptor; Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
[a.k.a. R-HSA-388396, PTH/PTHrP type I receptor, ENST00000449590]
4) '9606.ENSP00000371875':
NKX3-2 - Homeobox protein Nkx-3.2; Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity); Belongs to the NK-3 homeobox family.
[a.k.a. AF009801, NP_001180.1, HPA027564]
5) '9606.ENSP00000373600':
LRRK1 - Leucine rich repeat kinase 1; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.
[a.k.a. ENST00000531270, XP_011520318.1, ENSP00000433069]
6) '9606.RMRP':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000441765':
PTHLH - Parathyroid hormone-related protein; Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity o [...]
[a.k.a. R-HSA-388396, PTHRP, R-HSA-162582]
8) '9606.ENSP00000413720':
CDKN1C - Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life; Belongs to the CDI family.
[a.k.a. ENST00000250707, ENSP00000370101, R-HSA-69278]
9) '9606.ENSP00000275034':
PHIP - PH-interacting protein; Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.
[a.k.a. XP_016866479.1, XP_005248786, ABK76299.1]
10) '9606.ENSP00000433208':
PTH - Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
[a.k.a. R-HSA-388396, R-HSA-162582, R-HSA-373080]
