Your Input: | |||||
GATM | |||||
GAMT | |||||
SLC6A8 | |||||
OAT | |||||
EXD1 | |||||
HAPLN1 | |||||
PLPBP | |||||
LCMT2 | |||||
ASL | |||||
BTD |
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASL | GATM | ENSP00000307188 | ENSP00000379895 | Argininosuccinate lyase. | Glycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis; Belongs to the amidinotransferase family. | 0.891 |
ASL | OAT | ENSP00000307188 | ENSP00000357838 | Argininosuccinate lyase. | Ornithine aminotransferase, mitochondrial; Ornithine aminotransferase. | 0.990 |
GAMT | GATM | ENSP00000403536 | ENSP00000379895 | Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Important in nervous system development. | Glycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis; Belongs to the amidinotransferase family. | 0.997 |
GAMT | SLC6A8 | ENSP00000403536 | ENSP00000253122 | Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Important in nervous system development. | Sodium- and chloride-dependent creatine transporter 1; Required for the uptake of creatine in muscles and brain. | 0.945 |
GATM | ASL | ENSP00000379895 | ENSP00000307188 | Glycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis; Belongs to the amidinotransferase family. | Argininosuccinate lyase. | 0.891 |
GATM | GAMT | ENSP00000379895 | ENSP00000403536 | Glycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis; Belongs to the amidinotransferase family. | Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Important in nervous system development. | 0.997 |
GATM | SLC6A8 | ENSP00000379895 | ENSP00000253122 | Glycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis; Belongs to the amidinotransferase family. | Sodium- and chloride-dependent creatine transporter 1; Required for the uptake of creatine in muscles and brain. | 0.933 |
HAPLN1 | SLC6A8 | ENSP00000274341 | ENSP00000253122 | Hyaluronan and proteoglycan link protein 1; Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix. | Sodium- and chloride-dependent creatine transporter 1; Required for the uptake of creatine in muscles and brain. | 0.727 |
OAT | ASL | ENSP00000357838 | ENSP00000307188 | Ornithine aminotransferase, mitochondrial; Ornithine aminotransferase. | Argininosuccinate lyase. | 0.990 |
SLC6A8 | GAMT | ENSP00000253122 | ENSP00000403536 | Sodium- and chloride-dependent creatine transporter 1; Required for the uptake of creatine in muscles and brain. | Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Important in nervous system development. | 0.945 |
SLC6A8 | GATM | ENSP00000253122 | ENSP00000379895 | Sodium- and chloride-dependent creatine transporter 1; Required for the uptake of creatine in muscles and brain. | Glycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis; Belongs to the amidinotransferase family. | 0.933 |
SLC6A8 | HAPLN1 | ENSP00000253122 | ENSP00000274341 | Sodium- and chloride-dependent creatine transporter 1; Required for the uptake of creatine in muscles and brain. | Hyaluronan and proteoglycan link protein 1; Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix. | 0.727 |