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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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⤓ Mapping
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1) '9606.ENSP00000406191':
TRPV4 - Transient receptor potential cation channel subfamily V member 4; Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by heat, low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin- dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in t [...]
[a.k.a. ENST00000346520, R-HSA-3295583, NP_001170902.1]
2) '9606.ENSP00000406157':
PAPSS2 - Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2; Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. May have [...]
[a.k.a. SK2, R-HSA-2408522, R-HSA-3781865]
3) '9606.ENSP00000301873':
LTBP3 - Latent-transforming growth factor beta-binding protein 3; Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.
[a.k.a. R-HSA-2129379, ENST00000529371, LTBP3-221]
4) '9606.ENSP00000261978':
LTBP2 - Latent-transforming growth factor beta-binding protein 2; May play an integral structural role in elastic-fiber architectural organization and/or assembly. Belongs to the LTBP family.
[a.k.a. R-HSA-2129379, ENST00000329329, NP_000419]
5) '9606.RP11-261P24.2':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000440945':
PACSIN3 - Protein kinase C and casein kinase substrate in neurons protein 3; Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity).
[a.k.a. uc001ndx.4, XR_002957143, ENSP00000440945]
7) '9606.ENSP00000400852':
ZNF736 - Zinc finger protein 736; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
[a.k.a. B4DX44, NM_001170905, ENST00000493036]
8) '9606.ENSP00000461032':
ZNF594 - Zinc finger protein 594; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
[a.k.a. ENST00000315777, KIAA1871, zinc finger protein 594]
9) '9606.ENSP00000265174':
PAPSS1 - Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1; Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Required [...]
[a.k.a. U53447, PAPSS1-204, R-HSA-2408522]
10) '9606.ENSP00000265709':
ANK1 - Ankyrin-1; Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions.
[a.k.a. XM_017013324, XP_016868810, ENST00000358820]
