DISEASES

Disease-gene associations mined from literature

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Human genes for Peutz-Jeghers syndrome

Peutz-Jeghers syndrome [DOID:3852]

An intestinal disease characterized by melanocytic macules of the lips, buccal mucosa, and digits; multiple gastrointestinal hamartomatous polyps; and an increased risk of various neoplasms that has_material_basis_in heterozygous mutation in the serine/threonine kinase STK11 gene on chromosome 19p13.

Synonyms:  Peutz-Jeghers syndrome,  DOID:3852,  PeutzJeghers syndrome,  Peutz-Jeghers disease,  Peutz-Jeghers disorder ...

Linkouts:  OMIM

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.