DISEASES

Disease-gene associations mined from literature

Human genes for filarial elephantiasis

Filarial elephantiasis [DOID:12211]

A filariasis that is characterized by the thickening of the skin and underlying tissues, especially in the legs, male genitals and female breasts, caused by thread-like parasitic worms Wuchereria bancrofti, Brugia malayi or Brugia timori, which inhabit the lymphatics. These nematodes are transmitted by mosquitoes. Acute symptoms include fever, lymphadenitis, lymphangitis, funiculitis, and epididymitis. Chronic symptoms include abscesses, hyperkeratosis, polyarthritis, hydroceles, lymphedema, and elephantiasis.

Synonyms:  filarial elephantiasis,  DOID:12211,  filarial elephantiasises,  Bancroftian elephantiasis,  Bancroftian filarial chyluria ...