DISEASES

Disease-gene associations mined from literature

JensenLab

Human genes for immunodeficiency 60

Immunodeficiency 60 [DOID:0111954]

A combined T cell and B cell immunodeficiency characterized by variably decreased immunoglobulin production, decreased T-regulatory cells, overall impaired lymphocyte maturation, inflammatory bowel disease and recurrent sinopulmonary infections that has_material_basis_in heterozygous mutation in the BACH2 gene on chromosome 6q15.

Synonyms:  immunodeficiency 60,  DOID:0111954,  BACH2-related immunodeficiency and autoimmunity,  BRIDA,  IMD60 ...