DISEASES

Disease-gene associations mined from literature

JensenLab

Human genes for immunodeficiency 16

Immunodeficiency 16 [DOID:0111935]

A combined T cell and B cell immunodeficiency characterized by classic Kaposi sarcoma of childhood, poor T-cell recall immune responses, and decrease in the proportion of circulating memory B cells that has_material_basis_in homozygous or compound heterozygous mutation in the TNFRSF4 gene on chromosome 1p36.33.

Synonyms:  immunodeficiency 16,  DOID:0111935,  IMD16,  OX40 deficiency,  combined immunodeficiency due to OX40 deficiency ...