DISEASES

Disease-gene associations mined from literature

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Human genes for ACTH-independent macronodular adrenal hyperplasia

ACTH-independent macronodular adrenal hyperplasia [DOID:0111622]

A primary hyperaldosteronism characterized by multiple bilateral adrenocortical nodules that cause a striking enlargement of the adrenal gland and production of an excess of cortisol.

Synonyms:  ACTH-independent macronodular adrenal hyperplasia,  ACTHindependent macronodular adrenal hyperplasia,  ACTH-independent macronodular adrenal hyperplasias,  DOID:0111622,  ACTH-independent macronodular adrenocortical hyperplasia ...

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.