DISEASES

Disease-gene associations mined from literature

JensenLab

Human genes for autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6

Autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6 [DOID:0111519]

A chronic progressive external ophthalmoplegia characterized by muscle weakness, mainly affecting the lower limbs, external ophthalmoplegia, exercise intolerance and mtDNA deletions that has_material_basis_in heterozygous mutation in the DNA2 gene on chromosome 10q21.3.

Synonyms:  autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6,  DOID:0111519,  DNA2-related mitochondrial DNA deletion syndrome,  PEOA6,  autosomal dominant progressive external ophthalmoplegia 6 ...