DISEASES

Disease-gene associations mined from literature

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Human genes for amyotrophic lateral sclerosis-parkinsonism/dementia complex 1

Amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 [DOID:0111246]

A neurodegenerative disease characterized by chronic, progressive amyotrophic lateral sclerosis and parkinsonism-dementia. Susceptibility to this disease is influenced by heterozygous mutation in TRPM7 on 15q21.2.

Synonyms:  amyotrophic lateral sclerosis-parkinsonism/dementia complex 1,  amyotrophic lateral sclerosisparkinsonism/dementia complex 1,  DOID:0111246,  ALS-PDC,  amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam ...

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.