DISEASES

Disease-gene associations mined from literature

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Human genes for multicentric Castleman disease

Multicentric Castleman disease [DOID:0111152]

A Castleman disease characterized by systemic inflammatory symptoms, polyclonal lymphoproliferation, cytopenias, and multiple organ system dysfunction caused by a cytokine storm often including interleukin-6.

Synonyms:  multicentric Castleman disease,  DOID:0111152,  multicentric Castleman disorder,  multicentric Castleman syndrome,  multicentric Castleman diseases ...

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.