DISEASES

Disease-gene associations mined from literature

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Human genes for neurodegeneration with brain iron accumulation

Neurodegeneration with brain iron accumulation [DOID:0110734]

A neurodegenerative disease characterized by progressive iron accumulation in the basal ganglia and other regions of the brain, resulting in extrapyramidal movements, such as parkinsonism and dystonia.

Synonyms:  neurodegeneration with brain iron accumulation,  DOID:0110734,  neurodegeneration with brain iron accumulations,  NBIA

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.