DISEASES

Disease-gene associations mined from literature

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Human genes for hereditary diffuse gastric cancer

Hereditary diffuse gastric cancer [DOID:0080764]

A diffuse gastric cancer that is characterized by characterized by the development of diffuse (signet ring cell) gastric cancer at a young age, associated with germline heterozygous mutations of CDH1, MAP3K6 and CTNNA1 genes.

Synonyms:  hereditary diffuse gastric cancer,  DOID:0080764,  familial diffuse gastric cancer,  hereditary diffuse gastric cancers,  Familial diffuse cancer of stomach ...

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.